NAD+ 500MG

NAD+ (Nicotinamide Adenine Dinucleotide) is a coenzyme naturally occurring in all living cells and is a crucial molecule in biochemical processes. This product provides pure NAD+ in a 500mg concentration, intended for use in biochemical research studies.

Research Context

NAD+ plays a fundamental role in cellular metabolism, energy production, and redox homeostasis. It is a key molecule in several enzymatic reactions, including those involved in DNA repair, aging processes, and mitochondrial function. Researchers utilize NAD+ and its precursors (such as NMN or NR) to study its biochemical properties, effects on cellular aging models, and potential applications in biochemical and pharmacological research.

Research Overview

NAD+ is primarily found in its reduced form (NADH) during energy production, where it transfers electrons to other molecules. In its oxidized form (NAD+), it serves as a substrate for several enzymes, including PARP (Poly ADP Ribose Polymerase), SIRT (Sirtuins), and CD38. These enzymes are implicated in cellular stress responses, DNA repair, and longevity research. NAD+ levels decline with age, which has led to significant interest in its supplementation for research purposes to investigate mechanisms of aging and metabolic health.

Key Research Focus Areas

• Cellular Aging Studies: Research exploring NAD+ depletion’s impact on senescence, mitochondrial function, and lifespan extension in model organisms.
• DNA Repair Mechanisms: Investigations into how NAD+-dependent enzymes (e.g., PARP) contribute to genomic stability and cellular resilience.
• Metabolic Regulation: Studies examining NAD+ dynamics in metabolic pathways, including glucose and lipid metabolism, under various physiological and pathological conditions.
• Aging and Longevity: Research focused on NAD+ supplementation and its potential role in extending healthspan and lifespan in model systems.
• Biochemical Enzyme Assays: Use of NAD+ in enzymatic assays to study its interaction with sirtuins, CD38, and other NAD+-dependent proteins.

Caution and Compliance

This product is for research use only and is not intended for human or animal consumption. It is supplied as a pure chemical compound without additives or stabilizers for biochemical applications. Researchers must follow their institution’s guidelines for handling and storing NAD+ to ensure proper experimental conditions. Always ensure compliance with all relevant regulatory and ethical standards in research activities.

For research use only. Not for human or animal consumption.